The reaction of (2-oxo-2-phenyl-ethyl sulfanyl)-Acetic Acid with Chalcones: Double Michael Addition-Aldol Reaction Formation of Unexpected (5-Benzoyl-2-hydroxy-2,4-6-triphenyl-cyclohexyl) -phenyl-methanone
نویسندگان
چکیده
A greener approach one-pot reaction of (2-oxo-2-phenyl-ethyl sulfanyl)-acetic acid with chalcones in presence a base to afford an unexpected (5-Benzoyl-2-hydroxy-2,4-6-triphenyl-cyclohexyl) – phenyl-methanone product. The proceeds via sequential double Michael addition-aldol mediated three consecutive C-C bonds are formed one pot. procedure has short time, easy workup, and moderate yield products. structure all synthesized compounds was determined by using 1HNMR 13CNMR Spectral analysis.
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ژورنال
عنوان ژورنال: Oriental journal of chemistry
سال: 2022
ISSN: ['0970-020X', '2231-5039']
DOI: https://doi.org/10.13005/ojc/380521